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Microscopy reveals how psychedelics light up brains neuropathways Cornell Chronicle The Hopkins team have also conducted one of the two most recent studies on psilocybin for end-of-life depression and anxiety, which are discussed as a group below. Tagliazucchi et al. carried out a reanalysis of the previously published data from Carhart-Harris et al. . Their new analyses were prompted by a view that more sensitive and specific indices might help to develop a better understanding of the neurobiology of conscious states, and specifically that measures that include variance over time might be especially informative. They note that the brain has been described as a system resting in a critical point or transition zone between states of order and disorder (see references in Tagliazucchi et al., 2014). To test this hypothesis, the authors focused on variability in activity and functional connectivity parameters over time and presented empirical data that tested the hypothesis that brain ac...